Early Huntington's disease affects movements in transformed sensorimotor mappings

Boulet, C.; Lemay, M.; Bédard, M.A.; Chouinard, M.J.; Chouinard, S. et Richer, François (2005). « Early Huntington's disease affects movements in transformed sensorimotor mappings ». Brain and cognition, 57(3), pp. 236-243.

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Résumé

This study examined the effect of transformed visual feedback on movement control in Huntington’s disease (HD). Patients in the early stages of HD and controls performed aiming movements towards peripheral targets on a digitizing tablet using an indirect visual control of movement through a monitor and emphasizing precision. In a baseline condition, HD patients were slower but showed few precision problems in aiming. When visual feedback was inverted in both vertical and horizontal axes, patients showed problems in initial and terminal phases of movement where feedback is most critical. When visual feedback was inverted along a single axis as in a mirror-inversion, HD patients showed large deviations and over-corrections before adaptation. Adaptation was similar in both groups. These results suggest that HD impairs on-line error correction in novel movements.

Type:	Article de revue scientifique
Mots-clés ou Sujets:	Huntington's disease, Movement control
Unité d'appartenance:	Faculté des sciences humaines > Département de psychologie Instituts > Institut des sciences cognitives (ISC)
Déposé par:	Dr. François Richer
Date de dépôt:	12 juin 2008
Dernière modification:	01 nov. 2014 02:04
Adresse URL :	http://archipel.uqam.ca/id/eprint/660

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